Path ID: DB01235_MESH_D020734_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C035420 | Melevodopa | Drug |
| UniProt:P21728 | D(1A) dopamine receptor | Protein |
| UniProt:P21918 | D(1B) dopamine receptor | Protein |
| UniProt:P14416 | D(2) dopamine receptor | Protein |
| UniProt:P35462 | D(3) dopamine receptor | Protein |
| UniProt:P21917 | D(4) dopamine receptor | Protein |
| MESH:D004298 | Dopamine | ChemicalSubstance |
| GO:0061527 | Dopamine secretion, neurotransmission | BiologicalProcess |
| HP:0100022 | Abnormality of movement | PhenotypicFeature |
| MESH:D020734 | Parkinsonism | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Melevodopa | INCREASES ACTIVITY OF | D(1A) Dopamine Receptor |
| Melevodopa | INCREASES ACTIVITY OF | D(1B) Dopamine Receptor |
| Melevodopa | INCREASES ACTIVITY OF | D(2) Dopamine Receptor |
| Melevodopa | INCREASES ACTIVITY OF | D(3) Dopamine Receptor |
| Melevodopa | INCREASES ACTIVITY OF | D(4) Dopamine Receptor |
| D(4) Dopamine Receptor | POSITIVELY CORRELATED WITH | Dopamine |
| D(1A) Dopamine Receptor | POSITIVELY CORRELATED WITH | Dopamine |
| D(1A) Dopamine Receptor | POSITIVELY CORRELATED WITH | Dopamine |
| D(1B) Dopamine Receptor | POSITIVELY CORRELATED WITH | Dopamine |
| D(2) Dopamine Receptor | POSITIVELY CORRELATED WITH | Dopamine |
| D(3) Dopamine Receptor | POSITIVELY CORRELATED WITH | Dopamine |
| Dopamine | PARTICIPATES IN | Dopamine Secretion, Neurotransmission |
| Dopamine Secretion, Neurotransmission | NEGATIVELY CORRELATED WITH | Abnormality Of Movement |
| Abnormality Of Movement | MANIFESTATION OF | Parkinsonism |
Reference: