Path ID: DB01234_MESH_D000224_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D003907 | dexamethasone | Drug |
| UniProt:P04150 | Glucocorticoid receptor | Protein |
| GO:0034651 | cortisol biosynthetic process | BiologicalProcess |
| GO:0032342 | aldosterone biosynthetic process | BiologicalProcess |
| MESH:D000224 | Primary adrenocortical insufficiency | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Dexamethasone | POSITIVELY REGULATES | Glucocorticoid Receptor |
| Glucocorticoid Receptor | POSITIVELY CORRELATED WITH | Cortisol Biosynthetic Process |
| Glucocorticoid Receptor | POSITIVELY CORRELATED WITH | Aldosterone Biosynthetic Process |
| Cortisol Biosynthetic Process | NEGATIVELY CORRELATED WITH | Primary Adrenocortical Insufficiency |
| Aldosterone Biosynthetic Process | NEGATIVELY CORRELATED WITH | Primary Adrenocortical Insufficiency |
Reference: