Path ID: DB01220_MESH_D006501_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C042734 | Rifaximin | Drug |
| UniProt:P0A8V2 | DNA-directed RNA polymerase subunit beta | Protein |
| GO:0003899 | DNA-directed 5’-3’ RNA polymerase activity | MolecularActivity |
| GO:0006351 | Transcription, DNA-templated | BiologicalProcess |
| taxonomy:2 | Bacteria | OrganismTaxon |
| MESH:D000641 | Ammonia | ChemicalSubstance |
| MESH:D006501 | Hepatic encephalopathy | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Rifaximin | DECREASES ACTIVITY OF | Dna-Directed Rna Polymerase Subunit Beta |
| Dna-Directed Rna Polymerase Subunit Beta | POSITIVELY REGULATES | Dna-Directed 5’-3’ Rna Polymerase Activity |
| Dna-Directed 5’-3’ Rna Polymerase Activity | POSITIVELY CORRELATED WITH | Transcription, Dna-Templated |
| Transcription, Dna-Templated | IN TAXON | Bacteria |
| Bacteria | PRODUCES | Ammonia |
| Ammonia | CONTRIBUTES TO | Hepatic Encephalopathy |
Reference: