Path ID: DB01218_MESH_D016778_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C023768 | halofantrine | Drug |
| CHEBI:15430 | protoporphyrin | ChemicalSubstance |
| taxonomy:5833 | Plasmodium falciparum | OrganismTaxon |
| MESH:D016778 | Falciparum malaria | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Halofantrine | MOLECULARLY INTERACTS WITH | Protoporphyrin |
| Protoporphyrin | DISRUPTS | Plasmodium Falciparum |
| Plasmodium Falciparum | CAUSES | Falciparum Malaria |
Comment: Mechanism of action is unknown (https://en.wikipedia.org/wiki/Halofantrine#Pharmacology). Halofantrine is never used to prevent malaria, rather for treatment only due to its toxicity.
Reference: