Path ID: DB01210_MESH_D005902_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002040 | Levobunolol | Drug |
| UniProt:P08588 | Beta-1 adrenergic receptor | Protein |
| UniProt:P07550 | Beta-2 adrenergic receptor | Protein |
| MESH:D000242 | Cyclic AMP | ChemicalSubstance |
| UBERON:0010427 | ciliary processes | GrossAnatomicalStructure |
| UBERON:0001796 | aqueous humor of eyeball | GrossAnatomicalStructure |
| HP:0007906 | Ocular hypertension | PhenotypicFeature |
| MESH:D005902 | Glaucoma, Open-Angle | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Levobunolol | DECREASES ACTIVITY OF | Beta-1 Adrenergic Receptor |
| Levobunolol | DECREASES ACTIVITY OF | Beta-2 Adrenergic Receptor |
| Beta-1 Adrenergic Receptor | INCREASES ABUNDANCE OF | Cyclic Amp |
| Beta-2 Adrenergic Receptor | INCREASES ABUNDANCE OF | Cyclic Amp |
| Cyclic Amp | LOCATED IN | Ciliary Processes |
| Ciliary Processes | CORRELATED WITH | Aqueous Humor Of Eyeball |
| Aqueous Humor Of Eyeball | POSITIVELY CORRELATED WITH | Ocular Hypertension |
| Ocular Hypertension | MANIFESTATION OF | Glaucoma, Open-Angle |
Reference: