Path ID: DB01202_MESH_D004828_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C026098 | levetiracetam | Drug |
| UniProt:Q7L0J3 | Synaptic vesicle glycoprotein 2A | Protein |
| UniProt:Q00975 | Voltage-dependent N-type calcium channel subunit alpha-1B | Protein |
| GO:0007269 | neurotransmitter secretion | BiologicalProcess |
| GO:0098982 | GABA-ergic synapse | BiologicalProcess |
| MESH:D004828 | Simple partial seizure | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Levetiracetam | POSITIVELY REGULATES | Synaptic Vesicle Glycoprotein 2A |
| Synaptic Vesicle Glycoprotein 2A | INCREASES ACTIVITY OF | Gaba-Ergic Synapse |
| Gaba-Ergic Synapse | NEGATIVELY CORRELATED WITH | Simple Partial Seizure |
| Levetiracetam | NEGATIVELY REGULATES | Voltage-Dependent N-Type Calcium Channel Subunit Alpha-1B |
| Voltage-Dependent N-Type Calcium Channel Subunit Alpha-1B | POSITIVELY REGULATES | Neurotransmitter Secretion |
| Neurotransmitter Secretion | POSITIVELY CORRELATED WITH | Simple Partial Seizure |
Reference: