Path ID: DB01194_MESH_D005902_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C111827 | brinzolamide | Drug |
| UniProt:P00918 | Carbonic anhydrase 2 | Protein |
| GO:0015701 | bicarbonate transport | BiologicalProcess |
| UBERON:0001796 | aqueous humor of eyeball | GrossAnatomicalStructure |
| HP:0007906 | Ocular hypertension | PhenotypicFeature |
| MESH:D005902 | Glaucoma, Open-Angle | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Brinzolamide | NEGATIVELY REGULATES | Carbonic Anhydrase 2 |
| Carbonic Anhydrase 2 | POSITIVELY REGULATES | Bicarbonate Transport |
| Bicarbonate Transport | INCREASES ABUNDANCE OF | Aqueous Humor Of Eyeball |
| Aqueous Humor Of Eyeball | POSITIVELY CORRELATED WITH | Ocular Hypertension |
| Ocular Hypertension | MANIFESTATION OF | Glaucoma, Open-Angle |
Reference: