Path ID: DB01185_MESH_D009634_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D005474 | Fluoxymesterone | Drug |
| UniProt:P10275 | Androgen receptor | Protein |
| GO:0030521 | Androgen receptor signaling pathway | BiologicalProcess |
| GO:0046544 | Development of secondary male sexual characteristics | BiologicalProcess |
| MESH:D009634 | Noonan syndrome | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Fluoxymesterone | INCREASES ACTIVITY OF | Androgen Receptor |
| Androgen Receptor | POSITIVELY REGULATES | Androgen Receptor Signaling Pathway |
| Androgen Receptor Signaling Pathway | POSITIVELY CORRELATED WITH | Development Of Secondary Male Sexual Characteristics |
| Development Of Secondary Male Sexual Characteristics | NEGATIVELY CORRELATED WITH | Noonan Syndrome |
Comment: Fluoxymesterone is a synthetic androgen, or male hormone, similar to testosterone. No clear mechanism of action is found in literature evidences.
Reference: