Path ID: DB01173_MESH_D009128_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D009966 | Orphenadrine | Drug |
| UniProt:O15399 | Glutamate receptor ionotropic, NMDA 2D | Protein |
| UniProt:Q05586 | Glutamate receptor ionotropic, NMDA 1 | Protein |
| UniProt:O60391 | Glutamate receptor ionotropic, NMDA 3B | Protein |
| UniProt:Q8TCU5 | Glutamate receptor ionotropic, NMDA 3A | Protein |
| GO:0035249 | Synaptic transmission, glutamatergic | BiologicalProcess |
| MESH:D009128 | Spasticity | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Orphenadrine | DECREASES ACTIVITY OF | Glutamate Receptor Ionotropic, Nmda 2D |
| Orphenadrine | DECREASES ACTIVITY OF | Glutamate Receptor Ionotropic, Nmda 1 |
| Orphenadrine | DECREASES ACTIVITY OF | Glutamate Receptor Ionotropic, Nmda 3B |
| Orphenadrine | DECREASES ACTIVITY OF | Glutamate Receptor Ionotropic, Nmda 3A |
| Glutamate Receptor Ionotropic, Nmda 2D | POSITIVELY CORRELATED WITH | Synaptic Transmission, Glutamatergic |
| Glutamate Receptor Ionotropic, Nmda 1 | POSITIVELY CORRELATED WITH | Synaptic Transmission, Glutamatergic |
| Glutamate Receptor Ionotropic, Nmda 3B | POSITIVELY CORRELATED WITH | Synaptic Transmission, Glutamatergic |
| Glutamate Receptor Ionotropic, Nmda 3A | POSITIVELY CORRELATED WITH | Synaptic Transmission, Glutamatergic |
| Synaptic Transmission, Glutamatergic | POSITIVELY CORRELATED WITH | Spasticity |
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