Path ID: DB01167_MESH_D055744_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D017964 | Itraconazole | Drug |
| UniProt:B8N2C8 | Sterol 14-alpha demethylase | Protein |
| MESH:D004875 | Ergosterol | ChemicalSubstance |
| GO:0005886 | plasma membrane | BiologicalProcess |
| taxonomy:5059 | Aspergillus flavus | OrganismTaxon |
| MESH:D055744 | Invasive Pulmonary Aspergillosis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Itraconazole | DECREASES ACTIVITY OF | Sterol 14-Alpha Demethylase |
| Sterol 14-Alpha Demethylase | INCREASES ABUNDANCE OF | Ergosterol |
| Ergosterol | POSITIVELY CORRELATED WITH | Plasma Membrane |
| Plasma Membrane | IN TAXON | Aspergillus Flavus |
| Aspergillus Flavus | CAUSES | Invasive Pulmonary Aspergillosis |
Reference: