Path ID: DB01165_MESH_D014435_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D015242 | ofloxacin | Drug |
| InterPro:IPR013759 | DNA topoisomerase, type IIA, subunit B, C-terminal | GeneFamily |
| GO:0006265 | DNA topological change | BiologicalProcess |
| taxonomy:90370 | Salmonella enterica subsp. enterica serovar Typhi | OrganismTaxon |
| MESH:D014435 | Typhoid fever | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ofloxacin | NEGATIVELY REGULATES | Dna Topoisomerase, Type Iia, Subunit B, C-Terminal |
| Dna Topoisomerase, Type Iia, Subunit B, C-Terminal | POSITIVELY REGULATES | Dna Topological Change |
| Dna Topological Change | IN TAXON | Salmonella Enterica Subsp. Enterica Serovar Typhi |
| Salmonella Enterica Subsp. Enterica Serovar Typhi | CAUSES | Typhoid Fever |
Reference: