Path ID: DB01105_MESH_D009765_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C058254 | sibutramine | Drug |
| GO:0098810 | neurotransmitter reuptake | BiologicalProcess |
| MESH:D009638 | Norepinephrine | ChemicalSubstance |
| MESH:D004298 | Dopamine | ChemicalSubstance |
| MESH:D009638 | Norepinephrine | ChemicalSubstance |
| MESH:D012701 | Serotonin | ChemicalSubstance |
| HP:0002591 | Polyphagia | PhenotypicFeature |
| MESH:D009765 | Obesity | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Sibutramine | NEGATIVELY REGULATES | Neurotransmitter Reuptake |
| Neurotransmitter Reuptake | INCREASES ABUNDANCE OF | Dopamine |
| Neurotransmitter Reuptake | INCREASES ABUNDANCE OF | Norepinephrine |
| Neurotransmitter Reuptake | INCREASES ABUNDANCE OF | Serotonin |
| Dopamine | CORRELATED WITH | Polyphagia |
| Norepinephrine | CORRELATED WITH | Polyphagia |
| Serotonin | CORRELATED WITH | Polyphagia |
| Polyphagia | CONTRIBUTES TO | Obesity |
Reference: