Path ID: DB01086_MESH_D011537_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D001566 | benzocaine | Drug |
| UniProt:Q9Y5Y9 | Sodium channel protein type 10 subunit alpha | Protein |
| MESH:D012964 | Sodium | ChemicalSubstance |
| GO:0005248 | Voltage-gated sodium channel activity | BiologicalProcess |
| GO:0051899 | Membrane depolarization | BiologicalProcess |
| GO:0019228 | Neuronal action potential | BiologicalProcess |
| CL:0000198 | Pain receptor cell | Cell |
| GO:0019233 | Sensory perception of pain | BiologicalProcess |
| MESH:D011537 | Itching of skin | Drug |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Benzocaine | DECREASES ACTIVITY OF | Sodium Channel Protein Type 10 Subunit Alpha |
| Sodium Channel Protein Type 10 Subunit Alpha | PARTICIPATES IN | Voltage-Gated Sodium Channel Activity |
| Voltage-Gated Sodium Channel Activity | INCREASES TRANSPORT OF | Sodium |
| Sodium | POSITIVELY CORRELATED WITH | Membrane Depolarization |
| Membrane Depolarization | POSITIVELY REGULATES | Neuronal Action Potential |
| Neuronal Action Potential | OCCURS IN | Pain Receptor Cell |
| Pain Receptor Cell | PARTICIPATES IN | Sensory Perception Of Pain |
| Sensory Perception Of Pain | MANIFESTATION OF | Itching Of Skin |
Reference: