Path ID: DB01085_MESH_D005902_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D010862 | pilocarpine | Drug |
| InterPro:IPR000995 | Muscarinic acetylcholine receptor family | GeneFamily |
| GO:0006939 | smooth muscle contraction | BiologicalProcess |
| UBERON:0005969 | eye trabecular meshwork | GrossAnatomicalStructure |
| UBERON:0003956 | aqueous drainage system | GrossAnatomicalStructure |
| HP:0007906 | Ocular Hypertension | PhenotypicFeature |
| MESH:D005902 | Open-angle glaucoma | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Pilocarpine | INCREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor Family |
| Muscarinic Acetylcholine Receptor Family | POSITIVELY REGULATES | Smooth Muscle Contraction |
| Smooth Muscle Contraction | REGULATES | Eye Trabecular Meshwork |
| Eye Trabecular Meshwork | POSITIVELY REGULATES | Aqueous Drainage System |
| Aqueous Drainage System | NEGATIVELY CORRELATED WITH | Ocular Hypertension |
| Ocular Hypertension | MANIFESTATION OF | Open-Angle Glaucoma |
Reference: