Path ID: DB01083_MESH_D009765_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C055122 | orlistat | Drug |
| UniProt:P07098 | Gastric triacylglycerol lipase | Protein |
| UniProt:P16233 | Pancreatic triacylglycerol lipase | Protein |
| GO:0044241 | lipid digestion | BiologicalProcess |
| HP:0004324 | Increased body weight | PhenotypicFeature |
| MESH:D009765 | Obesity | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Orlistat | NEGATIVELY REGULATES | Gastric Triacylglycerol Lipase |
| Orlistat | NEGATIVELY REGULATES | Pancreatic Triacylglycerol Lipase |
| Gastric Triacylglycerol Lipase | POSITIVELY REGULATES | Lipid Digestion |
| Pancreatic Triacylglycerol Lipase | POSITIVELY REGULATES | Lipid Digestion |
| Lipid Digestion | POSITIVELY CORRELATED WITH | Increased Body Weight |
| Increased Body Weight | SUPERCLASS OF | Obesity |
Reference: