Path ID: DB01075_MESH_D003233_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D004155 | Diphenhydramine | Drug |
| UniProt:P35367 | Histamine H1 receptor | Protein |
| GO:0071420 | cellular response to histamine | BiologicalProcess |
| MESH:D006632 | Histamine | ChemicalSubstance |
| MESH:D006969 | Hypersensitivity, Immediate | Disease |
| MESH:D003233 | Conjunctivitis, Allergic | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Diphenhydramine | DECREASES ACTIVITY OF | Histamine H1 Receptor |
| Histamine H1 Receptor | POSITIVELY REGULATES | Cellular Response To Histamine |
| Cellular Response To Histamine | POSITIVELY CORRELATED WITH | Histamine |
| Histamine | PARTICIPATES IN | Hypersensitivity, Immediate |
| Hypersensitivity, Immediate | CONTRIBUTES TO | Conjunctivitis, Allergic |
Reference: