Path ID: DB01066_MESH_D011018_3
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C057710 | Cefditoren pivoxil | Drug |
| MESH:C073460 | Cefditoren | ChemicalSubstance |
| InterPro:IPR001460 | Penicillin-binding protein, transpeptidase | GeneFamily |
| GO:0009252 | Peptidoglycan biosynthetic process | BiologicalProcess |
| GO:0009273 | Peptidoglycan-based cell wall biogenesis | BiologicalProcess |
| taxonomy:1313 | Streptococcus pneumoniae | OrganismTaxon |
| MESH:D011018 | Pneumococcal pneumonia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Cefditoren Pivoxil | HAS METABOLITE | Cefditoren |
| Cefditoren | DECREASES ACTIVITY OF | Penicillin-Binding Protein, Transpeptidase |
| Penicillin-Binding Protein, Transpeptidase | POSITIVELY CORRELATED WITH | Peptidoglycan Biosynthetic Process |
| Peptidoglycan Biosynthetic Process | CONTRIBUTES TO | Peptidoglycan-Based Cell Wall Biogenesis |
| Peptidoglycan-Based Cell Wall Biogenesis | IN TAXON | Streptococcus Pneumoniae |
| Streptococcus Pneumoniae | CAUSES | Pneumococcal Pneumonia |
Comment: Cefditoren pivoxil is the pivaloyloxymethyl ester prodrug of cefditoren
Reference: