Path ID: DB01059_MESH_D004405_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D009643 | norfloxacin | Drug |
| UniProt:P43702 | topoisomerases II, IV | Protein |
| GO:0003746 | Translocation of EF-G | MolecularActivity |
| GO:0006260 | Bacterial DNA replication | BiologicalProcess |
| GO:0006412 | Bacterial Protein Synthesis | BiologicalProcess |
| taxonomy:622 | Shigella dysenteriae | OrganismTaxon |
| MESH:D004405 | Shigellosis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Norfloxacin | DECREASES ACTIVITY OF | Topoisomerases Ii, Iv |
| Norfloxacin | NEGATIVELY REGULATES | Translocation Of Ef-G |
| Topoisomerases Ii, Iv | PARTICIPATES IN | Bacterial Dna Replication |
| Translocation Of Ef-G | PRECEDES | Bacterial Protein Synthesis |
| Bacterial Dna Replication | OCCURS IN | Shigella Dysenteriae |
| Bacterial Protein Synthesis | OCCURS IN | Shigella Dysenteriae |
| Shigella Dysenteriae | CAUSES | Shigellosis |
Reference: