Path ID: DB01048_MESH_D015658_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C106538 | abacavir | Drug |
| CHEBI:64174 | carbovir triphosphate | ChemicalSubstance |
| UniProt:Q72547 | Reverse transcriptase/RNaseH | Protein |
| GO:0003964 | RNA-directed DNA polymerase activity | MolecularActivity |
| GO:0019079 | viral genome replication | BiologicalProcess |
| taxonomy:11676 | Human immunodeficiency virus 1 | OrganismTaxon |
| MESH:D015658 | Human immunodeficiency virus infection | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Abacavir | PRODUCES | Carbovir Triphosphate |
| Carbovir Triphosphate | DECREASES ACTIVITY OF | Reverse Transcriptase/Rnaseh |
| Reverse Transcriptase/Rnaseh | POSITIVELY REGULATES | Rna-Directed Dna Polymerase Activity |
| Rna-Directed Dna Polymerase Activity | POSITIVELY CORRELATED WITH | Viral Genome Replication |
| Viral Genome Replication | IN TAXON | Human Immunodeficiency Virus 1 |
| Human Immunodeficiency Virus 1 | CAUSES | Human Immunodeficiency Virus Infection |
Reference: