Path ID: DB01029_MESH_D003928_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C081309 | Irbesartan | Drug |
| UniProt:P30556 | Type-1 angiotensin II receptor | Protein |
| MESH:D000804 | Angiotensin II | ChemicalSubstance |
| MESH:D014661 | Vasoconstriction | Disease |
| GO:0045777 | Up regulation of blood pressure | BiologicalProcess |
| MESH:D003928 | Diabetic Nephropathies | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Irbesartan | DECREASES ACTIVITY OF | Type-1 Angiotensin Ii Receptor |
| Type-1 Angiotensin Ii Receptor | POSITIVELY CORRELATED WITH | Angiotensin Ii |
| Angiotensin Ii | CAUSES | Vasoconstriction |
| Vasoconstriction | CONTRIBUTES TO | Up Regulation Of Blood Pressure |
| Up Regulation Of Blood Pressure | AFFECTS RISK FOR | Diabetic Nephropathies |
Reference: