Path ID: DB01022_MESH_D006996_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D014812 | Phytomenadione | Drug |
| UniProt:P02818 | Osteocalcin | Protein |
| GO:0030282 | Bone mineralization | BiologicalProcess |
| MESH:D006996 | Hypocalcemia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Phytomenadione | INCREASES ACTIVITY OF | Osteocalcin |
| Osteocalcin | POSITIVELY REGULATES | Bone Mineralization |
| Bone Mineralization | NEGATIVELY CORRELATED WITH | Hypocalcemia |
Comment: Phytomenadione promotes calcification of bones and teeth and can be supplemented together with calcium sources in cases of hypocalcemia. Additionally phytomenadione may prevent arterial calcification in case of calcium supplementation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566462/
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