Path ID: DB01018_MESH_D001289_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D016316 | Guanfacine | Drug |
| UniProt:P08913 | Alpha-2A adrenergic receptor | Protein |
| MESH:D001289 | Attention deficit hyperactivity disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Guanfacine | INCREASES ACTIVITY OF | Alpha-2A Adrenergic Receptor |
| Alpha-2A Adrenergic Receptor | TREATS | Attention Deficit Hyperactivity Disorder |
Comment: The link between guanfacine’s molecular mechanism and it’s effect on the treatment of ADHD has not been determined
Reference: