Path ID: DB01004_MESH_D007635_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D015774 | Ganciclovir | Drug |
| MESH:D004247 | DNA | ChemicalSubstance |
| UniProt:P04293 | DNA polymerase catalytic subunit (Human herpesvirus 1) | Protein |
| GO:0019079 | Viral genome replication | BiologicalProcess |
| taxonomy:10298 | Human herpesvirus type 1 | OrganismTaxon |
| MESH:D007635 | Herpes simplex dendritic keratitis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ganciclovir | DISRUPTS | Dna |
| Ganciclovir | DECREASES ACTIVITY OF | Dna Polymerase Catalytic Subunit (Human Herpesvirus 1) |
| Dna | PARTICIPATES IN | Viral Genome Replication |
| Dna Polymerase Catalytic Subunit (Human Herpesvirus 1) | POSITIVELY REGULATES | Viral Genome Replication |
| Viral Genome Replication | IN TAXON | Human Herpesvirus Type 1 |
| Human Herpesvirus Type 1 | CAUSES | Herpes Simplex Dendritic Keratitis |
Reference: