Path ID: DB01003_MESH_D065631_1

db01003-mesh-d065631-1

Concepts

Identifier Name Type
MESH:D004205 cromoglicic acid Drug
UniProt:P25815 Protein S100-P Protein
GO:0043303 mast cell degranulation BiologicalProcess
GO:0043308 eosinophil degranulation BiologicalProcess
reactome:R-HSA-2454202 Allergen dependent IgE bound FCERI aggregation Pathway
GO:0002540 leukotriene production involved in inflammatory response BiologicalProcess
GO:0002441 histamine secretion involved in inflammatory response BiologicalProcess
MESH:D065631 Allergic rhinitis Disease

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Cromoglicic Acid DECREASES ACTIVITY OF Protein S100-P
Protein S100-P POSITIVELY CORRELATED WITH Mast Cell Degranulation
Protein S100-P POSITIVELY CORRELATED WITH Eosinophil Degranulation
Mast Cell Degranulation CAUSED BY Allergen Dependent Ige Bound Fceri Aggregation
Allergen Dependent Ige Bound Fceri Aggregation POSITIVELY CORRELATED WITH Histamine Secretion Involved In Inflammatory Response
Allergen Dependent Ige Bound Fceri Aggregation POSITIVELY CORRELATED WITH Leukotriene Production Involved In Inflammatory Response
Eosinophil Degranulation POSITIVELY CORRELATED WITH Leukotriene Production Involved In Inflammatory Response
Histamine Secretion Involved In Inflammatory Response POSITIVELY CORRELATED WITH Allergic Rhinitis
Leukotriene Production Involved In Inflammatory Response POSITIVELY CORRELATED WITH Allergic Rhinitis

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