Path ID: DB01001_MESH_D001986_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000420 | Salbutamol | Drug |
| UniProt:P07550 | Beta-2 adrenergic receptor | Protein |
| UniProt:B7Z2C7 | Adenylate cyclase | Protein |
| CHEBI:17489 | 3’,5’-cyclic AMP | ChemicalSubstance |
| HP:4000007 | Bronchoconstriction | PhenotypicFeature |
| MESH:D001986 | Bronchospasm | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Salbutamol | POSITIVELY REGULATES | Beta-2 Adrenergic Receptor |
| Beta-2 Adrenergic Receptor | POSITIVELY REGULATES | Adenylate Cyclase |
| Adenylate Cyclase | INCREASES ABUNDANCE OF | 3’,5’-Cyclic Amp |
| 3’,5’-Cyclic Amp | NEGATIVELY CORRELATED WITH | Bronchoconstriction |
| Bronchoconstriction | POSITIVELY CORRELATED WITH | Bronchospasm |
Reference: