Path ID: DB00996_MESH_D012148_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000077206 | Gabapentin | Drug |
| UniProt:P54289 | Voltage-dependent calcium channel subunit alpha-2/delta-1 | Protein |
| GO:0006936 | muscle contraction | BiologicalProcess |
| HP:0012531 | Pain | PhenotypicFeature |
| MESH:D012148 | Restless Legs Syndrome | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Gabapentin | DECREASES ACTIVITY OF | Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-1 |
| Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-1 | POSITIVELY REGULATES | Muscle Contraction |
| Muscle Contraction | POSITIVELY CORRELATED WITH | Pain |
| Pain | POSITIVELY CORRELATED WITH | Restless Legs Syndrome |
Reference: