Path ID: DB00975_MESH_D001281_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D004176 | Dipyridamole | Drug |
| UniProt:Q9Y233 | cAMP and cAMP-inhibited cGMP 3’,5’-cyclic phosphodiesterase 10A | Protein |
| UniProt:O76074 | cGMP-specific 3’,5’-cyclic phosphodiesterase | Protein |
| UniProt:P27815 | cAMP-specific 3’,5’-cyclic phosphodiesterase 4A | Protein |
| UniProt:P00813 | Adenosine deaminase | Protein |
| MESH:D000242 | Cyclic AMP | ChemicalSubstance |
| GO:0050482 | arachidonic acid secretion | BiologicalProcess |
| GO:0004796 | thromboxane-A synthase activity | MolecularActivity |
| GO:0070527 | Platelet aggregation | BiologicalProcess |
| CHEBI:16335 | adenosine | ChemicalSubstance |
| MESH:D001281 | Atrial fibrillation | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Dipyridamole | DECREASES ACTIVITY OF | Camp And Camp-Inhibited Cgmp 3’,5’-Cyclic Phosphodiesterase 10A |
| Dipyridamole | DECREASES ACTIVITY OF | Cgmp-Specific 3’,5’-Cyclic Phosphodiesterase |
| Dipyridamole | DECREASES ACTIVITY OF | Camp-Specific 3’,5’-Cyclic Phosphodiesterase 4A |
| Dipyridamole | DECREASES ACTIVITY OF | Adenosine Deaminase |
| Camp And Camp-Inhibited Cgmp 3’,5’-Cyclic Phosphodiesterase 10A | DECREASES ABUNDANCE OF | Cyclic Amp |
| Cgmp-Specific 3’,5’-Cyclic Phosphodiesterase | DECREASES ABUNDANCE OF | Cyclic Amp |
| Camp-Specific 3’,5’-Cyclic Phosphodiesterase 4A | DECREASES ABUNDANCE OF | Cyclic Amp |
| Adenosine Deaminase | DECREASES ABUNDANCE OF | Cyclic Amp |
| Cyclic Amp | NEGATIVELY REGULATES | Arachidonic Acid Secretion |
| Arachidonic Acid Secretion | NEGATIVELY REGULATES | Thromboxane-A Synthase Activity |
| Thromboxane-A Synthase Activity | PARTICIPATES IN | Platelet Aggregation |
| Dipyridamole | DECREASES UPTAKE OF | Adenosine |
| Adenosine | NEGATIVELY CORRELATED WITH | Platelet Aggregation |
| Platelet Aggregation | POSITIVELY CORRELATED WITH | Atrial Fibrillation |
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