Path ID: DB00973_MESH_D010437_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002707 | chlordiazepoxide | Drug |
| InterPro:IPR006028 | Gamma-aminobutyric acid A receptor/Glycine receptor alpha | GeneFamily |
| GO:0022851 | GABA-gated chloride ion channel activity | BiologicalProcess |
| GO:0060081 | membrane hyperpolarization | BiologicalProcess |
| GO:0007269 | neurotransmitter secretion | BiologicalProcess |
| GO:0001696 | gastric acid secretion | BiologicalProcess |
| HP:0100852 | Abnormal fear/anxiety-related behavior | PhenotypicFeature |
| MESH:D010437 | Peptic ulcer | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Chlordiazepoxide | NEGATIVELY CORRELATED WITH | Gastric Acid Secretion |
| Gastric Acid Secretion | POSITIVELY CORRELATED WITH | Peptic Ulcer |
| Chlordiazepoxide | INCREASES ACTIVITY OF | Gamma-Aminobutyric Acid A Receptor/Glycine Receptor Alpha |
| Gamma-Aminobutyric Acid A Receptor/Glycine Receptor Alpha | POSITIVELY REGULATES | Gaba-Gated Chloride Ion Channel Activity |
| Gaba-Gated Chloride Ion Channel Activity | POSITIVELY CORRELATED WITH | Membrane Hyperpolarization |
| Membrane Hyperpolarization | NEGATIVELY CORRELATED WITH | Neurotransmitter Secretion |
| Neurotransmitter Secretion | POSITIVELY CORRELATED WITH | Abnormal Fear/Anxiety-Related Behavior |
| Abnormal Fear/Anxiety-Related Behavior | AFFECTS RISK FOR | Peptic Ulcer |
Reference: