Path ID: DB00973_MESH_D000430_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002707 | chlordiazepoxide | Drug |
| InterPro:IPR006028 | Gamma-aminobutyric acid A receptor/Glycine receptor alpha | GeneFamily |
| GO:0022851 | GABA-gated chloride ion channel activity | BiologicalProcess |
| GO:0060081 | membrane hyperpolarization | BiologicalProcess |
| GO:0007269 | neurotransmitter secretion | BiologicalProcess |
| HP:0001289 | Confusion | PhenotypicFeature |
| HP:0000746 | Delusions | PhenotypicFeature |
| HP:0001337 | Tremor | PhenotypicFeature |
| HP:0000738 | Hallucinations | PhenotypicFeature |
| MESH:D000430 | Alcohol withdrawal delirium | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Chlordiazepoxide | INCREASES ACTIVITY OF | Gamma-Aminobutyric Acid A Receptor/Glycine Receptor Alpha |
| Gamma-Aminobutyric Acid A Receptor/Glycine Receptor Alpha | POSITIVELY REGULATES | Gaba-Gated Chloride Ion Channel Activity |
| Gaba-Gated Chloride Ion Channel Activity | POSITIVELY CORRELATED WITH | Membrane Hyperpolarization |
| Membrane Hyperpolarization | NEGATIVELY CORRELATED WITH | Neurotransmitter Secretion |
| Neurotransmitter Secretion | POSITIVELY CORRELATED WITH | Hallucinations |
| Neurotransmitter Secretion | POSITIVELY CORRELATED WITH | Tremor |
| Neurotransmitter Secretion | POSITIVELY CORRELATED WITH | Delusions |
| Neurotransmitter Secretion | POSITIVELY CORRELATED WITH | Confusion |
| Confusion | MANIFESTATION OF | Alcohol Withdrawal Delirium |
| Delusions | MANIFESTATION OF | Alcohol Withdrawal Delirium |
| Tremor | MANIFESTATION OF | Alcohol Withdrawal Delirium |
| Hallucinations | MANIFESTATION OF | Alcohol Withdrawal Delirium |
Reference: