Path ID: DB00966_MESH_D006973_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| DB:DB00966 | Telmisartan | Drug |
| UniProt:P37231 | Peroxisome proliferator-activated receptor gamma | Protein |
| UniProt:P30556 | Type-1 angiotensin II receptor | Protein |
| MESH:D000804 | Angiotensin II | ChemicalSubstance |
| MESH:D014661 | Vasoconstriction | Disease |
| GO:0045777 | Positive regulation of blood pressure | BiologicalProcess |
| MESH:D006973 | Hypertensive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Telmisartan | INCREASES ACTIVITY OF | Type-1 Angiotensin Ii Receptor |
| Telmisartan | INCREASES ACTIVITY OF | Peroxisome Proliferator-Activated Receptor Gamma |
| Peroxisome Proliferator-Activated Receptor Gamma | NEGATIVELY CORRELATED WITH | Positive Regulation Of Blood Pressure |
| Type-1 Angiotensin Ii Receptor | POSITIVELY CORRELATED WITH | Angiotensin Ii |
| Angiotensin Ii | POSITIVELY REGULATES | Vasoconstriction |
| Vasoconstriction | POSITIVELY CORRELATED WITH | Positive Regulation Of Blood Pressure |
| Positive Regulation Of Blood Pressure | POSITIVELY CORRELATED WITH | Hypertensive Disorder |
Reference: