Path ID: DB00938_MESH_D011656_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000068299 | salmeterol | Drug |
| UniProt:P07550 | Beta-2 adrenergic receptor | Protein |
| UniProt:B7Z2C7 | Adenylate cyclase | Protein |
| CHEBI:17489 | 3’,5’-cyclic AMP | ChemicalSubstance |
| GO:0044557 | relaxation of smooth muscle | BiologicalProcess |
| UBERON:0002185 | bronchus | GrossAnatomicalStructure |
| MESH:D011656 | Pulmonary emphysema | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Salmeterol | POSITIVELY REGULATES | Beta-2 Adrenergic Receptor |
| Beta-2 Adrenergic Receptor | POSITIVELY REGULATES | Adenylate Cyclase |
| Adenylate Cyclase | INCREASES ABUNDANCE OF | 3’,5’-Cyclic Amp |
| 3’,5’-Cyclic Amp | POSITIVELY CORRELATED WITH | Relaxation Of Smooth Muscle |
| Relaxation Of Smooth Muscle | LOCATED IN | Bronchus |
| Bronchus | AFFECTED BY | Pulmonary Emphysema |
Reference: