Path ID: DB00936_MESH_D010003_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D020156 | salicylic acid | Drug |
| UniProt:P23219 | Prostaglandin G/H synthase 1 | Protein |
| UniProt:P35354 | Prostaglandin G/H synthase 2 | Protein |
| GO:0001516 | prostaglandin biosynthetic process | BiologicalProcess |
| GO:0006954 | inflammatory response | BiologicalProcess |
| HP:0002829 | Arthralgia | PhenotypicFeature |
| HP:0001386 | Joint swelling | PhenotypicFeature |
| MESH:D010003 | Osteoarthritis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Salicylic Acid | DECREASES ACTIVITY OF | Prostaglandin G/H Synthase 1 |
| Salicylic Acid | DECREASES ACTIVITY OF | Prostaglandin G/H Synthase 2 |
| Prostaglandin G/H Synthase 1 | POSITIVELY REGULATES | Prostaglandin Biosynthetic Process |
| Prostaglandin G/H Synthase 2 | POSITIVELY REGULATES | Prostaglandin Biosynthetic Process |
| Prostaglandin Biosynthetic Process | POSITIVELY CORRELATED WITH | Inflammatory Response |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Arthralgia |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Joint Swelling |
| Arthralgia | MANIFESTATION OF | Osteoarthritis |
| Joint Swelling | MANIFESTATION OF | Osteoarthritis |
Reference: