Path ID: DB00921_MESH_D009293_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002047 | Buprenorphine | Drug |
| UniProt:P41145 | Kappa-type opioid receptor | Protein |
| HP:0000716 | Depression | PhenotypicFeature |
| HP:0033511 | Drug addiction | PhenotypicFeature |
| MESH:D009293 | Opioid-Related Disorders | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Buprenorphine | DECREASES ACTIVITY OF | Kappa-Type Opioid Receptor |
| Kappa-Type Opioid Receptor | POSITIVELY CORRELATED WITH | Depression |
| Kappa-Type Opioid Receptor | POSITIVELY CORRELATED WITH | Drug Addiction |
| Depression | POSITIVELY CORRELATED WITH | Opioid-Related Disorders |
| Drug Addiction | POSITIVELY CORRELATED WITH | Opioid-Related Disorders |
Reference: