Path ID: DB00915_MESH_D010300_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000547 | Amantadine | Drug |
| UniProt:P14416 | D(2) dopamine receptor | Protein |
| MESH:D004298 | Dopamine | ChemicalSubstance |
| GO:0061527 | Dopamine secretion, neurotransmission | BiologicalProcess |
| UBERON:0002038 | Substantia nigra | GrossAnatomicalStructure |
| MESH:D010300 | Parkinson’s disease | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Amantadine | INCREASES ACTIVITY OF | D(2) Dopamine Receptor |
| D(2) Dopamine Receptor | POSITIVELY CORRELATED WITH | Dopamine |
| Dopamine | POSITIVELY CORRELATED WITH | Dopamine Secretion, Neurotransmission |
| Dopamine Secretion, Neurotransmission | OCCURS IN | Substantia Nigra |
| Substantia Nigra | DISRUPTED BY | Parkinson’S Disease |
Reference: