Path ID: DB00908_MESH_D001281_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D011802 | quinidine | Drug |
| InterPro:PR001696 | Voltage gated sodium channel, alpha subunit | GeneFamily |
| GO:0061337 | cardiac conduction | BiologicalProcess |
| GO:0060048 | cardiac muscle contraction | BiologicalProcess |
| MESH:D001281 | Atrial fibrillation | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Quinidine | DISRUPTS | Voltage Gated Sodium Channel, Alpha Subunit |
| Voltage Gated Sodium Channel, Alpha Subunit | POSITIVELY REGULATES | Cardiac Conduction |
| Cardiac Conduction | POSITIVELY CORRELATED WITH | Cardiac Muscle Contraction |
| Cardiac Muscle Contraction | POSITIVELY CORRELATED WITH | Atrial Fibrillation |
Reference: