Path ID: DB00872_MESH_D007010_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C106389 | conivaptan | Drug |
| UniProt:P37288 | Vasopressin V1a receptor | Protein |
| UniProt:P30518 | Vasopressin V2 receptor | Protein |
| reactome:R-HSA-432040 | Vasopressin regulates renal water homeostasis via Aquaporins | Pathway |
| GO:0070295 | renal water absorption | BiologicalProcess |
| MESH:D007010 | Hyponatremia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Conivaptan | DECREASES ACTIVITY OF | Vasopressin V1A Receptor |
| Conivaptan | DECREASES ACTIVITY OF | Vasopressin V2 Receptor |
| Vasopressin V1A Receptor | PARTICIPATES IN | Vasopressin Regulates Renal Water Homeostasis Via Aquaporins |
| Vasopressin V2 Receptor | PARTICIPATES IN | Vasopressin Regulates Renal Water Homeostasis Via Aquaporins |
| Vasopressin Regulates Renal Water Homeostasis Via Aquaporins | POSITIVELY REGULATES | Renal Water Absorption |
| Renal Water Absorption | POSITIVELY CORRELATED WITH | Hyponatremia |
Reference: