Path ID: DB00869_MESH_D005902_1

db00869-mesh-d005902-1

Concepts

Identifier Name Type
MESH:C062765 dorzolamide Drug
UniProt:P00918 Carbonic anhydrase 2 Protein
GO:0015701 bicarbonate transport BiologicalProcess
UBERON:0001796 aqueous humor of eyeball GrossAnatomicalStructure
HP:0007906 Ocular Hypertension PhenotypicFeature
MESH:D005902 Open-angle glaucoma Disease

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Dorzolamide NEGATIVELY REGULATES Carbonic Anhydrase 2
Carbonic Anhydrase 2 POSITIVELY REGULATES Bicarbonate Transport
Bicarbonate Transport INCREASES ABUNDANCE OF Aqueous Humor Of Eyeball
Aqueous Humor Of Eyeball POSITIVELY CORRELATED WITH Ocular Hypertension
Ocular Hypertension MANIFESTATION OF Open-Angle Glaucoma

Reference: