Path ID: DB00858_MESH_D001943_1

db00858-mesh-d001943-1

Concepts

Identifier Name Type
MESH:C100263 Drostanolone Drug
UniProt:P10275 Androgen receptor Protein
GO:0030520 Intracellular estrogen receptor signaling pathway BiologicalProcess
GO:0008283 Cell population proliferation BiologicalProcess
MESH:D001943 Breast Neoplasms Disease

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Drostanolone INCREASES ACTIVITY OF Androgen Receptor
Androgen Receptor NEGATIVELY REGULATES Intracellular Estrogen Receptor Signaling Pathway
Intracellular Estrogen Receptor Signaling Pathway POSITIVELY REGULATES Cell Population Proliferation
Cell Population Proliferation POSITIVELY CORRELATED WITH Breast Neoplasms

Comment: Drostanolone, or dromostanolone, is an anabolic–androgenic steroid (AAS) of the dihydrotestosterone (DHT) group which was never marketed.

Reference: