Path ID: DB00839_MESH_D003924_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D014042 | tolazamide | Drug |
| UniProt:Q09428 | ATP-binding cassette sub-family C member 8 | Protein |
| UniProt:Q14654 | ATP-sensitive inward rectifier potassium channel 11 | Protein |
| GO:0030073 | insulin secretion | BiologicalProcess |
| HP:0003074 | Hyperglycemia | PhenotypicFeature |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Tolazamide | INCREASES ACTIVITY OF | Atp-Binding Cassette Sub-Family C Member 8 |
| Tolazamide | INCREASES ACTIVITY OF | Atp-Sensitive Inward Rectifier Potassium Channel 11 |
| Atp-Binding Cassette Sub-Family C Member 8 | PARTICIPATES IN | Insulin Secretion |
| Atp-Sensitive Inward Rectifier Potassium Channel 11 | PARTICIPATES IN | Insulin Secretion |
| Insulin Secretion | NEGATIVELY CORRELATED WITH | Hyperglycemia |
| Hyperglycemia | MANIFESTATION OF | Diabetes Mellitus, Type 2 |
Reference: