Path ID: DB00810_MESH_D001480_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D001712 | biperiden | Drug |
| UniProt:P11229 | Muscarinic acetylcholine receptor M1 | Protein |
| GO:0007271 | synaptic transmission, cholinergic | BiologicalProcess |
| HP:0002071 | Abnormality of extrapyramidal motor function | PhenotypicFeature |
| MESH:D001480 | Basal Ganglia Diseases | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Biperiden | NEGATIVELY REGULATES | Muscarinic Acetylcholine Receptor M1 |
| Muscarinic Acetylcholine Receptor M1 | POSITIVELY REGULATES | Synaptic Transmission, Cholinergic |
| Synaptic Transmission, Cholinergic | POSITIVELY CORRELATED WITH | Abnormality Of Extrapyramidal Motor Function |
| Abnormality Of Extrapyramidal Motor Function | MANIFESTATION OF | Basal Ganglia Diseases |
Comment: The disease is also known as Extrapyramidal disease as per the original file.
Reference: