Path ID: DB00804_MESH_D043183_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D004025 | Dicycloverine | Drug |
| UniProt:P20309 | Muscarinic acetylcholine receptor M3 | Protein |
| GO:1905144 | Response to acetylcholine | BiologicalProcess |
| GO:0120054 | Intestinal motility | BiologicalProcess |
| GO:0006939 | Smooth muscle contraction | BiologicalProcess |
| GO:0030421 | Defecation | BiologicalProcess |
| GO:0034776 | Response to histamine | BiologicalProcess |
| MESH:D043183 | Irritable bowel syndrome | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Dicycloverine | DECREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor M3 |
| Muscarinic Acetylcholine Receptor M3 | PARTICIPATES IN | Response To Acetylcholine |
| Response To Acetylcholine | POSITIVELY REGULATES | Smooth Muscle Contraction |
| Smooth Muscle Contraction | POSITIVELY REGULATES | Intestinal Motility |
| Smooth Muscle Contraction | POSITIVELY REGULATES | Defecation |
| Intestinal Motility | OCCURS IN | Irritable Bowel Syndrome |
| Defecation | OCCURS IN | Irritable Bowel Syndrome |
| Dicycloverine | NEGATIVELY REGULATES | Response To Histamine |
| Response To Histamine | POSITIVELY CORRELATED WITH | Irritable Bowel Syndrome |
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