Path ID: DB00795_MESH_D003093_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D012460 | sulfasalazine | Drug |
| UniProt:P09917 | Arachidonate 5-lipoxygenase | Protein |
| GO:0019370 | leukotriene biosynthesis | BiologicalProcess |
| GO:0006954 | inflammatory response | BiologicalProcess |
| MESH:D003093 | Ulcerative Colitis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Sulfasalazine | DECREASES ACTIVITY OF | Arachidonate 5-Lipoxygenase |
| Arachidonate 5-Lipoxygenase | POSITIVELY REGULATES | Leukotriene Biosynthesis |
| Leukotriene Biosynthesis | PART OF | Inflammatory Response |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Ulcerative Colitis |
Reference: