Path ID: DB00787_MESH_D020803_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000212 | aciclovir | Drug |
| Pfam:PF11590 | DNA polymerase catalytic subunit Pol | GeneFamily |
| GO:0039693 | viral DNA genome replication | BiologicalProcess |
| taxonomy:10298 | Human alphaherpesvirus 1 | OrganismTaxon |
| taxonomy:10310 | Human alphaherpesvirus 2 | OrganismTaxon |
| MESH:D020803 | Encephalitis due to Herpesvirus | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Aciclovir | NEGATIVELY REGULATES | Dna Polymerase Catalytic Subunit Pol |
| Dna Polymerase Catalytic Subunit Pol | POSITIVELY REGULATES | Viral Dna Genome Replication |
| Viral Dna Genome Replication | IN TAXON | Human Alphaherpesvirus 1 |
| Viral Dna Genome Replication | IN TAXON | Human Alphaherpesvirus 2 |
| Human Alphaherpesvirus 1 | CAUSES | Encephalitis Due To Herpesvirus |
| Human Alphaherpesvirus 2 | CAUSES | Encephalitis Due To Herpesvirus |
Reference: