Path ID: DB00781_MESH_D007634_1

db00781-mesh-d007634-1

Concepts

Identifier Name Type
MESH:D011112 Polymyxin B Drug
CHEBI:16412 lipopolysaccharide ChemicalSubstance
CHEBI:25051 Lipid A ChemicalSubstance
InterPro:IPR005025 NADPH-dependent FMN reductase-like GeneFamily
GO:0009274 peptidoglycan-based cell wall CellularComponent
GO:0045272 plasma membrane respiratory chain complex I CellularComponent
taxonomy:1280 Staphylococcus aureus OrganismTaxon
MESH:D007634 Keratitis Disease

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Polymyxin B DISRUPTS Lipopolysaccharide
Polymyxin B DISRUPTS Lipid A
Polymyxin B NEGATIVELY REGULATES Nadph-Dependent Fmn Reductase-Like
Lipopolysaccharide LOCATED IN Peptidoglycan-Based Cell Wall
Lipid A LOCATED IN Peptidoglycan-Based Cell Wall
Nadph-Dependent Fmn Reductase-Like PART OF Plasma Membrane Respiratory Chain Complex I
Peptidoglycan-Based Cell Wall IN TAXON Staphylococcus Aureus
Plasma Membrane Respiratory Chain Complex I IN TAXON Staphylococcus Aureus
Staphylococcus Aureus CAUSES Keratitis

Reference: