Path ID: DB00775_MESH_D054058_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000077466 | Tirofiban | Drug |
| UniProt:P08514 | Integrin alpha-IIb | Protein |
| UniProt:P05106 | Integrin beta-3 | Protein |
| GO:0070527 | platelet aggregation | BiologicalProcess |
| HP:0004420 | Arterial thrombosis | PhenotypicFeature |
| MESH:D054058 | Acute Coronary Syndrome | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Tirofiban | DECREASES ACTIVITY OF | Integrin Alpha-Iib |
| Tirofiban | DECREASES ACTIVITY OF | Integrin Beta-3 |
| Integrin Alpha-Iib | POSITIVELY REGULATES | Platelet Aggregation |
| Integrin Beta-3 | POSITIVELY REGULATES | Platelet Aggregation |
| Platelet Aggregation | POSITIVELY CORRELATED WITH | Arterial Thrombosis |
| Arterial Thrombosis | POSITIVELY CORRELATED WITH | Acute Coronary Syndrome |
Reference: