Path ID: DB00774_MESH_D004487_1

Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D006857 | hydroflumethiazide | Drug |
| UniProt:P55017 | Solute carrier family 12 member 3 | Protein |
| GO:0070294 | renal sodium ion absorption | BiologicalProcess |
| GO:0003092 | renal water retention | BiologicalProcess |
| MESH:D004487 | Edema | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Hydroflumethiazide | DECREASES ACTIVITY OF | Solute Carrier Family 12 Member 3 |
| Solute Carrier Family 12 Member 3 | POSITIVELY REGULATES | Renal Sodium Ion Absorption |
| Renal Sodium Ion Absorption | POSITIVELY CORRELATED WITH | Renal Water Retention |
| Renal Water Retention | POSITIVELY CORRELATED WITH | Edema |
Reference: