Path ID: DB00766_MESH_D014552_1

db00766-mesh-d014552-1

Concepts

Identifier Name Type
MESH:D019818 clavulanic acid Drug
InterPro:IPR012338 Beta-lactamase/transpeptidase-like GeneFamily
GO:0008800 beta-lactamase activity MolecularActivity
taxonomy:562 Escherichia coli OrganismTaxon
MESH:D014552 Urinary tract infectious disease Disease

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Clavulanic Acid NEGATIVELY REGULATES Beta-Lactamase/Transpeptidase-Like
Beta-Lactamase/Transpeptidase-Like POSITIVELY REGULATES Beta-Lactamase Activity
Beta-Lactamase Activity IN TAXON Escherichia Coli
Escherichia Coli CAUSES Urinary Tract Infectious Disease

Comment: The drug is not effective by itself as an antibiotic and it can be combined with penicillin-group antibiotics.

Reference: