Path ID: DB00766_MESH_D011018_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D019818 | clavulanic acid | Drug |
| InterPro:IPR012338 | Beta-lactamase/transpeptidase-like | GeneFamily |
| GO:0008800 | beta-lactamase activity | MolecularActivity |
| taxonomy:1313 | Streptococcus pneumoniae | OrganismTaxon |
| MESH:D011018 | Pneumococcal pneumonia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Clavulanic Acid | NEGATIVELY REGULATES | Beta-Lactamase/Transpeptidase-Like |
| Beta-Lactamase/Transpeptidase-Like | POSITIVELY REGULATES | Beta-Lactamase Activity |
| Beta-Lactamase Activity | IN TAXON | Streptococcus Pneumoniae |
| Streptococcus Pneumoniae | CAUSES | Pneumococcal Pneumonia |
Comment: The drug is not effective by itself as an antibiotic and it can be combined with penicillin-group antibiotics.
Reference: