Path ID: DB00747_MESH_D015878_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D012601 | Scopolamine | Drug |
| UniProt:P11229 | Muscarinic acetylcholine receptor M1 | Protein |
| UniProt:P08172 | Muscarinic acetylcholine receptor M2 | Protein |
| UniProt:P20309 | Muscarinic acetylcholine receptor M3 | Protein |
| UniProt:P08173 | Muscarinic acetylcholine receptor M4 | Protein |
| UniProt:P08912 | Muscarinic acetylcholine receptor M5 | Protein |
| GO:1905144 | Response to acetylcholine | BiologicalProcess |
| HP:0011499 | Dilated pupil | PhenotypicFeature |
| MESH:D015878 | Mydriasis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Scopolamine | DECREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor M1 |
| Scopolamine | DECREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor M2 |
| Scopolamine | DECREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor M3 |
| Scopolamine | DECREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor M4 |
| Scopolamine | DECREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor M5 |
| Muscarinic Acetylcholine Receptor M1 | PARTICIPATES IN | Response To Acetylcholine |
| Muscarinic Acetylcholine Receptor M2 | PARTICIPATES IN | Response To Acetylcholine |
| Muscarinic Acetylcholine Receptor M3 | PARTICIPATES IN | Response To Acetylcholine |
| Muscarinic Acetylcholine Receptor M4 | PARTICIPATES IN | Response To Acetylcholine |
| Muscarinic Acetylcholine Receptor M5 | PARTICIPATES IN | Response To Acetylcholine |
| Response To Acetylcholine | NEGATIVELY CORRELATED WITH | Dilated Pupil |
| Dilated Pupil | MANIFESTATION OF | Mydriasis |
Comment: Contraindication
Reference: