Path ID: DB00741_MESH_D016410_1

db00741-mesh-d016410-1

Concepts

Identifier Name Type
MESH:D006854 hydrocortisone Drug
UniProt:P04150 Glucocorticoid receptor Protein
UniProt:P04083 Annexin A1 Protein
UniProt:P47712 Cytosolic phospholipase A2 Protein
UniProt:P23219 Prostaglandin G/H synthase 1 Protein
UniProt:P35354 Prostaglandin G/H synthase 2 Protein
GO:0019370 leukotriene biosynthetic process BiologicalProcess
GO:0001516 prostaglandin biosynthetic process BiologicalProcess
GO:0006954 inflammatory response BiologicalProcess
HP:0000988 Skin rash PhenotypicFeature
HP:0000989 Pruritus PhenotypicFeature
MESH:D016410 Lymphoma, T-Cell, Cutaneous Disease

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Hydrocortisone INCREASES ACTIVITY OF Glucocorticoid Receptor
Glucocorticoid Receptor INCREASES ACTIVITY OF Annexin A1
Glucocorticoid Receptor DECREASES ACTIVITY OF Prostaglandin G/H Synthase 1
Glucocorticoid Receptor DECREASES ACTIVITY OF Prostaglandin G/H Synthase 2
Annexin A1 DECREASES ACTIVITY OF Cytosolic Phospholipase A2
Prostaglandin G/H Synthase 1 POSITIVELY REGULATES Prostaglandin Biosynthetic Process
Prostaglandin G/H Synthase 2 POSITIVELY REGULATES Prostaglandin Biosynthetic Process
Cytosolic Phospholipase A2 POSITIVELY REGULATES Leukotriene Biosynthetic Process
Cytosolic Phospholipase A2 POSITIVELY REGULATES Prostaglandin Biosynthetic Process
Leukotriene Biosynthetic Process POSITIVELY CORRELATED WITH Inflammatory Response
Prostaglandin Biosynthetic Process POSITIVELY CORRELATED WITH Inflammatory Response
Inflammatory Response POSITIVELY CORRELATED WITH Skin Rash
Inflammatory Response POSITIVELY CORRELATED WITH Pruritus
Skin Rash MANIFESTATION OF Lymphoma, T-Cell, Cutaneous
Pruritus MANIFESTATION OF Lymphoma, T-Cell, Cutaneous

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